Primacy and recency effects were preserved as indexed, respectively, by larger recall of the first and last words in relation to adjacent items. Flunitrazepam promoted a global amnestic effect, impairing recall in all serial positions except the last words (recency effect). This study evaluated the acute effects of flunitrazepam (1.0 mg 1.3 mg) and placebo in healthy volunteers on immediate and delayed free recall of word lists considering serial positions as well as semantic relations between words inserted in the middle of the lists (e.g. Although it is widely known that benzodiazepines impair episodic memory, few studies have investigated their effects upon specific processes involved in free recall.
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